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International Studies in Phenomenology and Philosophy

Book | Chapter

224566

Psychological impact of genetic testing

David T Miller

pp. 585-604

Abstract

News reports about how our genes affect many aspects of our life and health are increasing in both frequency and complexity. The last several years have seen amazing progress in our understanding of human genetics. The completion of the Human Genome Project in 2003 brought this issue into the mainstream more than any other single event (Collins et al 2003). Perhaps contrary to expectations, this milestone created more questions than it answered. Certainly, knowledge of the human genome sequence has increased the pace of genetic discovery for many diseases, but translating discoveries into patient care applications is not always straightforward.One way that genetic disease information can be harnessed in clinical medicine is through genetic testing. In the coming years, information about our genes will lead to the routine use of diagnostic testing, based on genetic markers for common diseases such as asthma, coronary artery disease, and diabetes. Genetic tests for these diseases may lead to substantive changes in medical management depending on the results. However, many of the genetic changes associated with these disorders have only a small risk effect, and a person may need to inherit several of these 'small effect" genes to develop the condition. These are called complex genetic diseases, and the reader is referred to recent reviews that discuss how to understand and apply the information from such studies in clinical care (Attia et al. 2009a, 2009b, 2009c; Fontanarosa et al. 2008).

Publication details

Published in:

Miller Thomas W. (2010) Handbook of stressful transitions across the lifespan. Dordrecht, Springer.

Pages: 585-604

DOI: 10.1007/978-1-4419-0748-6_29

Full citation:

Miller David T (2010) „Psychological impact of genetic testing“, In: T. W. Miller (ed.), Handbook of stressful transitions across the lifespan, Dordrecht, Springer, 585–604.