Metodo

International Studies in Phenomenology and Philosophy

Book | Chapter

184322

Clinical studies of social neuroscience

a lesion model approach

Fiona Kumfor Jessica L. Hazelton François-Laurent De Winter

pp. 255-296

Abstract

Understanding the neurobiological basis of complex human behaviors is a key aim for social neuroscience. Examining clinical populations with relatively circumscribed brain damage and related behavioral deficits can provide insights into brain regions which are necessary for abilities such as face processing, emotion recognition, theory of mind, and empathy. In this review, we reflect on the emerging body of evidence which combines experimental behavioral studies and neuroimaging analysis techniques in clinical groups, with a focus on four progressive neurodegenerative disorders: behavioral-variant frontotemporal dementia, semantic dementia, Huntington's disease, and Alzheimer's disease. These clinical syndromes are characterized by divergent patterns of neurodegeneration and variable degrees of impairment in social cognition and social behavior. Here, we review the paradigms which have been employed and the current patterns of findings in these syndromes and discuss how this line of research informs our understanding of the "social brain." In addition, we consider how our conception of these clinical phenotypes has changed, as aspects of social cognition have been incorporated into diagnostic and prognostic frameworks. Finally, we propose potential avenues for future research in these syndromes to address outstanding social neuroscience questions.

Publication details

Published in:

Ibáñez Agustín, Sedeño Lucas, García Adolfo M (2017) Neuroscience and social science: the missing link. Dordrecht, Springer.

Pages: 255-296

DOI: 10.1007/978-3-319-68421-5_12

Full citation:

Kumfor Fiona, Hazelton Jessica L., De Winter François-Laurent (2017) „Clinical studies of social neuroscience: a lesion model approach“, In: A. Ibáñez, L. Sedeño & A.M. García (eds.), Neuroscience and social science, Dordrecht, Springer, 255–296.