Within the life sciences, dis/ability is a continuous topic. The life sciences produce knowledge about individuals, classifying certain states as "disabled' and "non-disabled'. The discourses in specific disciplines are not independent from the discourse of everyday knowledge, or from the discourses that are constructed via popular culture. Below we will analyze how popular culture deals with the topic of dis/ability. Therefore, we will rely on theories that discuss the construction of dis/ability not as an essential given but as an on-going process that ascribes certain meanings to certain somatic and psychic phenomena. We start by contrasting three different models of "disability', after which we will describe the connection between the modern biological and medical discourses and the "freak shows' in the eighteenth and nineteenth centuries. Freak shows were one essential element to allow specific bodily attributes to be highlighted as "abnormal'. Not only in such shows, but also in all kinds of popular culture, individuals marked as "disabled' can be found. We will highlight the circumstances which led to the possibility of using "disability' in such a sense at all. Afterwards we will analyze what stereotypes are reproduced again and again. Finally, on the one hand we will discuss possibilities to think about "disability' beyond the discursive connotation of a lack or deficiency. One the other hand we will question the opportunities to disrupt the seemingly fixed dichotomy between "disabled' and "non-disabled' as well as the technologisation of disability in current media representations.