This article aims to investigate the relationship between music and Mimmo Paladino s figurative work throughout his career. Starting as a painter of silence, an artist finding shelter in silence to paint, Paladino then engaged in an increasingly dense dialogue with the art of sounds. He is convinced that the creation of music stemming from tonal harmony is parallel to the creation of the work of art originated from formal harmony, and believes that the elements of his compositions can be compared to counterpoints, notes, intervals, rhythms and musical harmonies. It is a long and complex path that led - and this is recent history - to the two collaborations with the non-musician Brian Eno, whose works this article will extensively dwell on.